Donald Trump sfoga la tensione dei processi giudiziari nel junk food

Gaza, l’Idf colpisce il nord della Striscia. Dall’inizio dell’offensiva israeliana oltre 35mila vittimeLinea dura di Schillaci, il governo sta pensando a restrizioni sul fumo all'apertoConte su Delmastro e Donzelli: "Creato un precedente pericoloso"

Denise Ragusa, Autore a Notizie.itCovid: infezione accelera invecchiamento,Guglielmo studio svela come di Adnkronos   30-07-2024 - 15:08 Link copiato #iubenda-cs-banner .iub_ts_bc:not(.iubenda-custom-content) *,#iubenda-cs-banner [class*=" iub"],#iubenda-cs-banner [class^=iub],.iubenda-tp-btn:not([data-tp-nostyle]){ 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(Adnkronos Salute) - Il Covid accelera l'invecchiamento biologico, una conseguenza a lungo termine dell'infezione anche in forma poco o per nulla sintomatica, favorita dall'infiammazione e dallo stress ossidativo. E il fenomeno riguarda soprattutto gli uomini. Questa la conclusione di uno studio del team interdisciplinare Medicina del lavoro dell'azienda Ospedale - Università di Padova, pubblicato sul "Journal of Molecular Sciences". La ricerca, guidata dalla professoressa Sofia Pavanello del Dipartimento di Scienze cardio-toraco-vascolari e Sanità pubblica dell'Università di Padova, è stata effettuata su 76 operatori sanitari dell'azienda ospedaliera contagiati nella prima ondata e poco o per nulla sintomatici. Per ognuno sono stati raccolti dati su demografia, stile di vita, storia medica ed esposizione ambientale e occupazionale, e tutti sono stati sottoposti a un esame clinico con test di funzionalità respiratoria e valutazione cardiaca, a valutazione della loro capacità lavorativa e test di biochimica di base, profili immunologici, biomarcatori di infiammazione e analisi dell'invecchiamento biologico."Poiché il campione analizzato è statisticamente rappresentativo dell'intera popolazione che ha contratto il Covid-19 con sintomi lievi o assenti, i risultati offrono importanti indicazioni per la salute pubblica, suggerendo strategie di gestione personalizzate e interventi di supporto per le persone più suscettibili alle conseguenze a lungo termine del virus", sottolinea Pavanello. L'équipe ha analizzato i parametri ematochimici tra cui indicatori di infiammazione, come interleuchina 6 e proteina C-reattiva, per verificare se lo stato infiammatorio persistesse dopo un anno dall’infezione. Sono stati esaminati i livelli di un marker molecolare di invecchiamento, la DnamAge. "Abbiamo riscontrato che l'aumento della DnamAge, oltre a essere associato alla durata dell’infezione - spiega Pavanello - era in relazione a un declino della funzionalità polmonare, della variabilità della frequenza cardiaca e una bassa frequenza cardiaca media. Un aumento della DnamAge indica un invecchiamento biologico accelerato, aggravato da fattori come l'infezione da Sars-CoV-2. Il campione preso in esame mostra un aumento della DnamAge con una riduzione della capacità respiratoria e della frequenza cardiaca media un anno dopo il contagio rispetto alla fase post-acuta, evidenziando l'impatto delle infezioni sull'invecchiamento biologico. La prima evidenza emersa dallo studio è che il monitoraggio della capacità respiratoria, della frequenza cardiaca e la Hrv, e il mantenimento degli stessi attraverso interventi mirati, potrebbero mitigare l'accelerazione dell'invecchiamento". Non solo. "Dai test clinici e dai campioni biologici emerge che un numero alto del campione (il 30%) ha sperimentato sintomi persistenti come difficoltà respiratoria (dispnea) e problemi cognitivi (problemi di concentrazione, memoria e ansia) fino a un anno dopo l'infezione", prosegue. Infatti "a un anno dal contagio si è riscontrato un invecchiamento biologico accelerato nelle cellule dell'espettorato rispetto ai leucociti del sangue e alle cellule nasali. Questa evidenza suggerisce un tessuto polmonare particolarmente vulnerabile anche in soggetti contagiati con poca o nulla sintomatologia da Covid-19. In termini di significatività - conclude Pavanello - la ricerca indica che questo invecchiamento biologico si associa maggiormente al genere maschile, confermando le statistiche sulla longevità maggiore del genere femminile e suggerendo anche strategie di prevenzione specifiche per genere; alla presenza di malattie croniche quali disturbi muscoloscheletrici, ernia del disco spinale, malattie gastrointestinali, malattie endocrine, diabete, malattie respiratorie e tumori. Altro dato importante è che, a parità di contagio e sintomi, chi presenta glicemia alta e alti livelli di Ldl (colesterolo cattivo) ha un maggior rischio di invecchiare più velocemente". di Adnkronos   30-07-2024 - 15:08 Link copiato Commenti Leggi la Netiquette

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