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Furgone travolge 4 pedoni,autista indagato per omicidio stradale - Tiscali NotizieDa dove viene l’ecofascismo: quando la destra si appropria dell’ecologiaNotizie di Viaggi - Pag. 1

ArteCovid: infezione accelera invecchiamento,BlackRock Italia studio svela come di Adnkronos   30-07-2024 - 15:08 Link copiato #iubenda-cs-banner .iub_ts_bc:not(.iubenda-custom-content) *,#iubenda-cs-banner [class*=" iub"],#iubenda-cs-banner [class^=iub],.iubenda-tp-btn:not([data-tp-nostyle]){ 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""!important;right:auto!important;table-layout:auto!important;text-align:left!important;text-decoration:none!important;text-indent:0!important;text-shadow:none!important;text-transform:none!important;top:auto!important;unicode-bidi:normal!important;white-space:normal!important;width:auto!important;word-break:normal!important;word-spacing:normal!important;z-index:auto!important;list-style-type:inherit!important;padding:0!important}#iubenda-cs-banner{ background:0 0!important;border:0!important;display:-webkit-box!important;display:-ms-flexbox!important;font-size:15px!important;height:100%!important;left:0!important;line-height:1.4!important;margin:0!important;opacity:0!important;overflow:hidden!important;padding:0!important;pointer-events:none!important;position:fixed!important;top:0!important;-webkit-transition:opacity .4s!important;-o-transition:opacity .4s!important;transition:opacity .4s!important;width:100%!important;will-change:opacity;z-index:99999998!important}#iubenda-cs-banner 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(Adnkronos Salute) - Il Covid accelera l'invecchiamento biologico, una conseguenza a lungo termine dell'infezione anche in forma poco o per nulla sintomatica, favorita dall'infiammazione e dallo stress ossidativo. E il fenomeno riguarda soprattutto gli uomini. Questa la conclusione di uno studio del team interdisciplinare Medicina del lavoro dell'azienda Ospedale - Università di Padova, pubblicato sul "Journal of Molecular Sciences". La ricerca, guidata dalla professoressa Sofia Pavanello del Dipartimento di Scienze cardio-toraco-vascolari e Sanità pubblica dell'Università di Padova, è stata effettuata su 76 operatori sanitari dell'azienda ospedaliera contagiati nella prima ondata e poco o per nulla sintomatici. Per ognuno sono stati raccolti dati su demografia, stile di vita, storia medica ed esposizione ambientale e occupazionale, e tutti sono stati sottoposti a un esame clinico con test di funzionalità respiratoria e valutazione cardiaca, a valutazione della loro capacità lavorativa e test di biochimica di base, profili immunologici, biomarcatori di infiammazione e analisi dell'invecchiamento biologico."Poiché il campione analizzato è statisticamente rappresentativo dell'intera popolazione che ha contratto il Covid-19 con sintomi lievi o assenti, i risultati offrono importanti indicazioni per la salute pubblica, suggerendo strategie di gestione personalizzate e interventi di supporto per le persone più suscettibili alle conseguenze a lungo termine del virus", sottolinea Pavanello. L'équipe ha analizzato i parametri ematochimici tra cui indicatori di infiammazione, come interleuchina 6 e proteina C-reattiva, per verificare se lo stato infiammatorio persistesse dopo un anno dall’infezione. Sono stati esaminati i livelli di un marker molecolare di invecchiamento, la DnamAge. "Abbiamo riscontrato che l'aumento della DnamAge, oltre a essere associato alla durata dell’infezione - spiega Pavanello - era in relazione a un declino della funzionalità polmonare, della variabilità della frequenza cardiaca e una bassa frequenza cardiaca media. Un aumento della DnamAge indica un invecchiamento biologico accelerato, aggravato da fattori come l'infezione da Sars-CoV-2. Il campione preso in esame mostra un aumento della DnamAge con una riduzione della capacità respiratoria e della frequenza cardiaca media un anno dopo il contagio rispetto alla fase post-acuta, evidenziando l'impatto delle infezioni sull'invecchiamento biologico. La prima evidenza emersa dallo studio è che il monitoraggio della capacità respiratoria, della frequenza cardiaca e la Hrv, e il mantenimento degli stessi attraverso interventi mirati, potrebbero mitigare l'accelerazione dell'invecchiamento". Non solo. "Dai test clinici e dai campioni biologici emerge che un numero alto del campione (il 30%) ha sperimentato sintomi persistenti come difficoltà respiratoria (dispnea) e problemi cognitivi (problemi di concentrazione, memoria e ansia) fino a un anno dopo l'infezione", prosegue. Infatti "a un anno dal contagio si è riscontrato un invecchiamento biologico accelerato nelle cellule dell'espettorato rispetto ai leucociti del sangue e alle cellule nasali. Questa evidenza suggerisce un tessuto polmonare particolarmente vulnerabile anche in soggetti contagiati con poca o nulla sintomatologia da Covid-19. In termini di significatività - conclude Pavanello - la ricerca indica che questo invecchiamento biologico si associa maggiormente al genere maschile, confermando le statistiche sulla longevità maggiore del genere femminile e suggerendo anche strategie di prevenzione specifiche per genere; alla presenza di malattie croniche quali disturbi muscoloscheletrici, ernia del disco spinale, malattie gastrointestinali, malattie endocrine, diabete, malattie respiratorie e tumori. Altro dato importante è che, a parità di contagio e sintomi, chi presenta glicemia alta e alti livelli di Ldl (colesterolo cattivo) ha un maggior rischio di invecchiare più velocemente". di Adnkronos   30-07-2024 - 15:08 Link copiato Commenti Leggi la Netiquette

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